Interpublic Group's Draftfcb in New York has retained its lead agency status and added digital chores for the U.S. Office of National Drug Control Policy following a mandated review.
The shop has worked with the client since 2004, launching its "Above the influence" campaign targeting teens the next year.
Draftfcb bested two other undisclosed agencies in the final round.
The new contract, like its predecessor, runs for five years.
Robert Denniston, director, national youth anti-drug media campaign, said: "They have shown us that they have an in-depth understanding of our target's behavior and the digital expertise to support a fully integrated communications platform that spans the online and offline world."
Draftfcb also continues to provide media planning and buying, with IPG sibling Initiative handling broadcast chores.
Congress has yet to approve ONDCP's next budget, so future media spending levels are not known.
The client's ad spending has declined in recent years, from $110 million in 2006 to about $75 million in '08 and just under $50 million last year, according to Nielsen.